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That’s much earlier than previouslyg thought, suggesting that treatment would be more effectivse if startedin middle-aged people, beforre onset of the disease, according to researchers in the . The studty followed 815 healthy people ages 21 to 97 with and without the APOE e4 a key risk factor for for up to14 years. Memory and thinking tests were used to comparrcognitive performance. About one out in four peopld have at least one copy ofthe gene, while 2 percent have two inherited from both parents and increasinbg risk. Alzheimer’s disease affects about 10 percent of peopled over age 65 and almos halfover 85.
Researchers from several institutions in theArizon Alzheimer’s Consortium collaborated on the including Arizona State University, Banner Alzheimer’s Barrow Neurological Institute, Sun Health Research Institute, Translationa Genomics Research Institute and University of The National Institute on Aging and the state of Arizonw provided funding. “This study highlightsd the ideathat Alzheimer’s disease is a progressive disorderr that likely begins well before clinical said Creighton Phelps, director of the Alzheimer’s Disease Researc Center program for the National Institute on “Additional research is needed to identify those at high geneticf risk and develop methods to delay disease Researchers, however, do not recommend using brain imaging or cognitive tests to predicgt risk.
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